Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation ...

Recent clinical studies have suggested that phenylacetylglutamine (PAGln), a novel gut microbial metabolite, can mechanistically modulate patients' risk of developing cardiovascular disease (CVD) and ...

Nerve fibers within melanomas can slow their growth, according to a study led by Weill Cornell Medicine investigators. The ...

However, a new study has identified a surprising “brake.” Investigating melanoma in mouse models, the team discovered that sympathetic nerves, the same ones responsible for the “fight-or-flight” ...

Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered the ...