To choose the best lead candidates during drug and antibody screening, scientists characterize a molecule’s binding properties, such as kinetics and affinity. Robust assay design reduces experimental ...
Evaluation of Chimeric Antigen Receptor Design To Identify Affinity and Spatial Binding Requirements
Chimeric antigen receptors (CARs) are artificial immunoreceptors that drive T cell-mediated tumor destruction. CAR-modified T cells have demonstrated unprecedented clinical success, leading to six FDA ...
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