A problem for biopharmaceutical companies comes as degraded proteins lead to ineffective and possibly dangerous medicines for their clients. Drug companies work on formulation development to protect ...

Nearly half of all drug shortages in 2022 were caused by quality issues or manufacturing delays, according to the Center for Drug Evaluation and Research (CDER). Evaluating the critical quality ...

Aggregation represents one of the most significant obstacles to the development of protein-based pharmaceuticals. During drug formulation, protein aggregation can impact product quality in terms of ...

An important parameter is the aggregation pattern when exposed to thermal stress, as this can give us a better understanding as needed for problem-solving during formulation development. To assess the ...

WOBURN, Mass.--(BUSINESS WIRE)--ReForm Biologics, a pharmaceutical technology company developing innovative biologic formulations to improve drug delivery and manufacturing, expanded its patent ...

New research demonstrates novel drug discovery paradigm to target the aggregation of the Tau protein linked to the onset of Alzheimer's and other related neurodegenerative diseases. Dementia and other ...

Vectura Limited has signed an agreement with GlaxoSmithKline plc (GSK) to collaborate on evaluating Vectura's Aerocine and associated powder formulation technologies in dry powder inhaler devices for ...

WuXi Biologics, a leading global contract research, development, and manufacturing organization (CRDMO), announced the launch of WuXiHigh2.0, a high-throughput formulation development platform ...

Abstract and Introduction Characteristics and Contributors to Drug Formulation Errors Recommendations for Reducing Patient Risk From Errors With Dose Formulations Summary References Characteristics ...

With topical formulations, it may be possible to deliver the active ingredient to a specific site and avoid first-pass metabolism, changing drug concentrations in the bloodstream and patient-specific ...

Researchers at the University of Colorado Anschutz Medical Campus have helped confirm the dosing, safety and effectiveness of a drug formulation designed for treating children with human ...