Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

Scientists discovered a novel self-perpetuating cancer mechanism in the lung microenvironment, wherein EGFR-driven lung adenocarcinoma cells exploit lung-resident macrophages -- remodeling them to ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood cells that defend the body by killing microbes, removing dead cells and ...