Sensory ataxic neuropathy with dysarthria and ophthalmoparesis (SANDO) is a rare phenotype resulting from pathogenic variants of mitochondrial DNA polymerase gamma (POLG). We modeled a novel POLG ...

Dysarthria is a collective term for a group of speech disorders that occur as a result of muscle weakness. People with dysarthria have neurological damage that weakens the muscles necessary for speech ...

The toxic effects of metronidazole include ataxia, peripheral neuropathy, and seizures. 1 There have been two reported cases in which abnormalities of the dentate nucleus on magnetic resonance imaging ...

Autosomal dominantly inherited spinocerebellar ataxias (SCAs) are a heterogeneous group of neurodegenerative disorders primarily affecting the cerebellum. Genetically, 26 different loci have been ...

Medically reviewed by Nicholas R. Metrus, MD Key Takeaways Dysarthria and anarthria are speech disorders caused by brain damage affecting the muscles that control speech.Conditions such as stroke, ...