Apart from respiratory symptoms, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of coronavirus disease 2019 (COVID-19) pandemic, causes neurological symptoms, ...
Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death. A ...
Axons surrounding amyloid plaques swell, but what goes wrong inside, and with what consequences, remains murky. Using high-resolution imaging techniques, scientists led by Jaime Grutzendler at Yale ...
This is a preview. Log in through your library . Abstract KIF1A is a kinesin superfamily motor protein that transports synaptic vesicle precursors in axons. Cargo binding stimulates the dimerization ...
This is a preview. Log in through your library . Abstract Axon injury is a hallmark of many neurodegenerative diseases, often resulting in neuronal cell death and functional impairment. Dual leucine ...
Axons are the brain’s information highways, transporting cellular cargo, chemical signals, and electrical impulses to other cells. These “roads” are typically depicted as smooth and cylindrical, with ...
Researchers have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled. The study focuses on neuronal growth and migration: ...
The neuron’s inner scaffold, once viewed as static support, now looks like a gatekeeper. Research findings are available ...
Thought LeaderDr. Federico Dajas-BailadorHead of Axon Biology Lab University of Nottingham UK After a recent visit to ELRIGs Drug Discovery 2023, News-Medical sits down with Dr. Federico ...