We have long been told a simple story about reward: Dopamine is the "wanting" molecule that drives us toward goals, and ...

One part of the basal ganglia, known as the nucleus accumbens (NAc), is composed of medium spiny neurons (MSNs). The MSNs, in which the dopamine D1 receptor (D1R) and dopamine D2 receptor (D2R) ...

Add Yahoo as a preferred source to see more of our stories on Google. If you’ve ever watched someone steamroll others, take credit they didn’t earn, or charm their way out of accountability—and still ...

People who are depressed very often show reduced interest in experiencing or obtaining pleasure, a symptom called anhedonia that research has traced to dysfunction in the brain’s reward system. In ...

In today's fast-paced world, the realms of fitness and gaming have captured the imaginations and routines of millions. The psychological aspects that underlie these two seemingly disparate activities ...

In addition to their weight loss benefits, GLP-1 RAs also act on neural circuits involved in appetite, impulse control, and ...

Researchers discover that the phosphorylation of a newly identified protein kinase substrate downstream of the dopamine signaling pathway regulates the brain reward behavior. The nucleus accumbens, ...