Lab-scale production of medicarpin in yeast heralds another manufacturing option for this natural anti-tumor agent.

An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance ...

Researchers identify the crucial protein for controlling the biosynthesis of steroidal glycoalkaloids and saponins in plants of the genus Solanum and for the first time demonstrate the ecological role ...

Biosynthesis specialist Antheia has topped off its series C funding with a second close, adding $24 million more to its haul.

The cancer drug paclitaxel has captured the imaginations of chemists for decades, in part because of its complex polycyclic core with an oxetane ring. Although scientists have synthesized the molecule ...

Researchers discover enzyme prototype for formation of ecologically and pharmaceutically important tropone compounds. Microorganisms produce natural products, for example, as disease-causing virulence ...

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin ...

By reconstructing a non-natural metabolic route in Escherichia coli, the researchers demonstrated that simple sugars can be biologically converted into lauryl glucoside through the coordinated ...

Floral scent is a defining trait for many ornamental plants, yet the genetic logic behind fragrance production often remains ...

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the ...