Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers at the University of Basel have now discovered that these skeletal cells do not just ...

In a recent study, Associate Professor Makoto Ikeya (Department of Clinical Application) and his team of researchers successfully established a method to generate jawbone-like organoids (mini-organs) ...

Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists at the University Medical Center Mainz have now shown how chronic ...

If you have ever broken a bone, you quickly learn two things: it hurts a lot, and bones are living tissue that takes time to heal, but they do heal. A fractured femur, for instance, may take six ...

Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...

Tooth loss and bone degeneration are problems that modern medicine still struggles to fix. Data from the National Bone Health Policy Institute shows that 10 million Americans over the age of 50 have ...