Background Psoriatic disease has a complex effect on bone metabolism, resulting in both pathological bone formation and bone resorption. However, microstructural changes in cortical and trabecular ...

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential ...

A multisite, international phase 2 trial evaluating the investigational drug garetosmab has shown that it reduced soft-tissue flare-ups significantly and prevented new areas of abnormal bone formation ...

Periodontitis is characterized by the loss of teeth resulting from inflammation of gums due to bacterial infections. The susceptibility to such bone loss disorders increases with age. The expression ...

Researchers at King's College London have discovered that an immune protein best known for protecting the body against ...

Heterotopic ossification (HO) is a common post-surgery condition where bone abnormally forms within soft tissues. A new study out of Mass General Brigham assesses the viability of a simple blood test ...

BRISBANE, Calif.--(BUSINESS WIRE)--āshibio, a privately held biotechnology company developing novel therapeutics for the treatment of bone and connective tissue disorders, exited stealth mode today ...

Researchers reveal that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and ...