A buildup of a structural protein called F-actin inside aging brain cells appears to cripple the cellular waste-clearing machinery that keeps neurons healthy, according to a study in Drosophila fruit ...

The generation of these cellular models for the study of diseases based on reprogrammed human cells is well established in pre-clinical studies - 2D cultures or organs-on-chip systems (OoCs) - and ...

The cost of bringing a new drug to the market has recently been estimated by Forbes Magazine at $5 billion. This figure derives in large part from high attrition rates in the drug development pipeline ...

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