Abnormal mesolimbic control of cortical cholinergic activity has been hypothesized to contribute to the cognitive symptoms of schizophrenia. Stimulation of NMDA receptors in nucleus accumbens (NAC) ...

An impressive data set that appeared yesterday in Neuron shows that a specific M1 muscarinic receptor agonist can reverse both cognitive deficits as well as the amyloid and tau pathology in the ...

This is a preview. Log in through your library . Abstract Tests were made for use-dependent plasticity in the cholinergic projections to hippocampus. Transient infusion of the cholinergic agonist ...

Walter Moraes, MD, PhD; Dalva Poyares, MD, PhD; Lucia Sukys-Claudino, MD; Christian Guilleminault, MD, PhD; Sergio Tufik, MD, PhD In summary our results support the concept that cholinergic ...