The New England Journal of Medicine

Azithromycin to Reduce Mortality — An Adaptive Cluster-Randomized Trial

Twice-yearly mass distribution of azithromycin to children is a promising intervention to reduce childhood mortality in sub-Saharan Africa. The World Health Organization recommended restricting ...
Nature

Cluster Randomized Trials and Statistical Methods

Cluster randomized trials (CRTs) represent a pivotal design in evaluating public health and clinical interventions where individuals are grouped into clusters (such as schools, hospitals or ...
ascopubs.org

A Pragmatic Cluster-Randomized Trial of a Standing Order Entry Intervention for Colony-Stimulating Factor Use Among Patients at Intermediate Risk for Febrile Neutropenia

Impact of an Interdisciplinary Goals-of-Care Program Among Medical Inpatients at a Comprehensive Cancer Center During the COVID-19 Pandemic: A Propensity Score Analysis TrACER was a cluster randomized ...
The New England Journal of Medicine

Decolonization in Nursing Homes to Prevent Infection and Hospitalization

We performed a cluster-randomized trial of universal decolonization as compared with routine-care bathing in nursing homes. The trial included an 18-month baseline period and an 18-month intervention ...
European Medical Journal

Mobile Instant Messaging for Smoking Cessation Falls Short

Cluster RCT finds mobile instant messaging exercise reminders did not significantly boost lab-verified smoking cessation at 6 months.
The Lancet

Universal school-based transdiagnostic interventions to improve mental health and wellbeing among Chinese adolescents: a two-group, cluster-randomised controlled trial

The reduction in depression and anxiety symptoms 3 months after completing ten AMHSP sessions indicates a slow but meaningful benefit of the programme and supports the potential of a low-intensity, ...
BMJ Global Health

Impact of cooking with liquefied petroleum gas compared with traditional cooking practices on perinatal and early neonatal mortality: the Poriborton cluster randomised ...

Objective To determine whether liquefied petroleum gas (LPG) can reduce perinatal mortality in a setting with high reliance on biomass fuels for cooking.Design Community-based two-arm parallel cluster ...