When a ribosome cruises along messenger RNA (mRNA), it may stall at a particular codon, depending on which codons are nearby. In other words, codon context can influence the efficiency with which mRNA ...
Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein engineering.
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...
AZoLifeSciences on MSN
Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
Cells working with an expanded genetic code could make more diverse medicines. A new study shows scientists are within striking distance. One of modern biologists' most ambitious goals is to learn how ...
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