Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

Scientists have recently been learning more about the importance of small bits of circular genetic material known as extrachromosomal DNA (ecDNA). These little circles of DNA can hitch a ride with ...

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments ...

A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor ...

G4 and R-loop signals at the indicated genomic locus. Both G4s and R-loops accumulate in cells where the resolution of G4 knots is defective (red). Not all DNA looks like the familiar twisted ladder.

RIVERSIDE, Calif. -- A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings ...

Viral DNA that is usually dismissed when sequencing the human genome could help to uncover useful information about complex ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...