Once disregarded as “junk DNA,” scientists now know that this molecular dark matter is crucial for determining gene activity ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...

Deep-learning model decodes the regulatory effects of DNA changes ...

It could transform our understanding of why diseases develop and the medicines needed to treat them, says researchers.

Psoriasis is a common inflammatory skin disease linked to several long-term health conditions, such as heart disease, ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

DNA can be thought of as a vast library that stores all genetic information. Cells do not use this information all at once. Instead, they copy only the necessary parts into RNA, which is then used to ...

What do your genes have to do with growing old? Quite a lot. But is it due to the actual DNA, or the way those genes are expressed? KPBS sci-tech reporter Thomas Fudge has more on new research that ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

By Tarun Sai Lomte Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s ...

Researchers reckon it could dramatically accelerate understanding of how DNA influences disease, cancer, and drug discovery.

DeepMind’s AlphaGenome AI model could help solve the problem of predicting how variations in noncoding DNA shape gene ...