ascopubs.org

DNA-Repair Gene Polymorphisms Predict Favorable Clinical Outcome Among Patients With Advanced Squamous Cell Carcinoma of the Head and Neck Treated With Cisplatin-Based ...

Clinical Activity of Pertuzumab (rhuMAb 2C4), a HER Dimerization Inhibitor, in Advanced Ovarian Cancer: Potential Predictive Relationship With Tumor HER2 Activation Status A polymerase chain ...
Nature

Genetic Polymorphisms and Treatment Outcomes in Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer (NSCLC) remains one of the leading causes of cancer-related mortality worldwide. Genetic polymorphisms—particularly single nucleotide polymorphisms (SNPs)—in genes that ...
The Scientist

How Did Natural Selection Shape Human Genes?

Researchers constructed a phylogenetic tree based upon human mitochondrial DNA (mtDNA) variation. A branch bifurcates whenever they found an additional polymorphism. At the top of the inverted tree is ...
ascopubs.org

Association of DNA Repair Gene Polymorphisms With Response to Platinum-Based Doublet Chemotherapy in Patients With Non–Small-Cell Lung Cancer

Second Malignancy Risks After Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia: Differences by Lymphoma Subtype In total, 640 patients with NSCLC who received platinum-based doublet ...
National Academies of Sciences%2c Engineering%2c and Medicine

Making Sense of Complexity: Summary of the Workshop on Dynamical Modeling of Complex Biomedical Systems

One of the major themes brought out by the workshop was the interplay between theory and data, but the discussions in preceding chapters do not mention how much data must be dealt with. In fact, the ...