Sermorelin, a synthetic analog of growth hormone–releasing hormone (GHRH 1–29), has long attracted scientific interest due to its structural fidelity to the endogenous GHRH fragment responsible for in ...
This specific 1-29 sequence is often referred to as the "functional fragment" because it contains the essential binding domain required to activate GHRH receptors in the pituitary gland.
Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...
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Feeling "off?" Your endocrine system might be why
This article was reviewed by Felix Gussone, MD. Key Takeaways: Your endocrine system regulates many bodily functions, from ...
New review reveals how non-genomic estrogen signaling undermines treatment response and fuels tumor progression Hormone receptor–positive breast ...
Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...
Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic ...
Peptide hormones and bile acids shaping immune tolerance of the liver: implications and applications
The exceptional immune tolerance of the liver is, in part, mediated by entero-pancreatic endocrine factors that enter the portal vein at elevated levels. These endocrine factors signal via cAMP, ...
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