Researchers have identified a cellular mechanism that is critical in maintaining normal cell function. They examined the function of TRAMP, a protein complex involved in the processing of RNA or ...

Researchers participating in the Enzyme Function Initiative (EFI) have used a computationally rich metabolite-docking strategy to sift through a protein’s potential metabolic partners and predict its ...

Fitting a key into a lock may seem like a simple task, but researchers are using a method that involves testing thousands of keys to unlock the functions of enzymes, and their findings could open the ...

CHAMPAIGN, Ill. — A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers ...

Doctors have long treated heart attacks, improved asthma symptoms and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins ...

Synthetic biology is a growing field of research that is aiming to create a new kind of organism. Engineering synthetic proteins that can perform simple cellular functions as they would in real life ...

The function of the glycolytic enzyme hexokinase 1 differs depending on its location within the cell, according to a Northwestern Medicine study published in Molecular Cell. The enzyme uses different ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...

Fitting a key into a lock may seem like a simple task, but researchers at Texas A&M University are using a method that involves testing thousands of keys to unlock the functions of enzymes, and their ...