In a recent study, led by corresponding author, Anna-Maria Liphardt, PhD, of the Rheumatology and Immunology Department at Friedrich-Alexander-Universität Erlangen-Nürnberg and the ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Amyotrophic lateral sclerosis and frontotemporal dementia are heterogeneous diseases that are difficult to fully model in mice. One of the more common forms is caused by hexanucleotide repeat ...

Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM). An interlinked net of proteins and sugars that surrounds brain cells, the ...

Liver fibrosis is characterized by the excessive deposition of extracellular matrix, a process primarily driven by activated hepatic stellate cells ...

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...

Despite its compact structure—composed of only three amino acids—this endogenous tripeptide has been repeatedly situated at ...

Biofilm-resident bacteria and fungi are significantly more tolerant to conventional antibiotics. The extracellular polymeric substance matrix acts as a ...

Discover the link between fascia and chronic pain. Learn how gentle myofascial release and tissue hydration offer lasting ...

New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage regeneration. Using extracellular vesicles derived from menstrual blood stromal ...