No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

Study offers molecular explanation for long-standing observation that certain diseases occur more often or more severely in different sexes. Complement component 4 (C4) genes protect against the ...

The complement system is part of the body's immune system to fight pathogens and remove cell debris; its role in two autoimmune diseases and a mental disorder is a surprise Variants in a gene of the ...

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes ...

Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...

REDWOOD CITY, Calif. & RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--Kriya Therapeutics, Inc., a fully integrated company pioneering novel technologies and therapeutics in gene therapy, today ...

The US Food and Drug Administration (FDA) has granted Fast Track Designation to Complement Therapeutics’ CTx001, the ...

This knowledge would help identify individuals who could benefit from early detection programmes, which are essential for a ...