Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

The ability to control gene expression across a wide range is crucial for many fields, including bioengineering, disease ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure. Disruptions in the rhythms of these clocks, as with ...

Less than 2% of the genome codes for proteins; the rest, once called 'junk DNA', contains regulatory elements. Researchers ...