Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when ...

How does our DNA store the massive amount of information needed to build a human being? And what happens when it's stored incorrectly? Jesse Dixon, MD, Ph.D., has spent years studying the way this ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

A research team has developed the "SUPER (Synthetic Upcycling Platform for Engineering Regulators)" platform, which ...

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

urning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when it's ...

CRISPRgenee is a new method that combines gene silencing and cutting to improve loss-of-function studies in human cells. (Nanowerk News) The 2020 Nobel Prize in Chemistry was awarded for the ...

Cell and gene therapies, or CGT, have come a long way since they were first introduced. In the last few decades, both cell therapy ...