Silencing mRNA expression in dendritic cells did not impair T‑cell priming, including for SARS‑CoV‑2 antigens, suggesting that cross‑presentation by other cell types is sufficient to initiate immunity ...

Add Yahoo as a preferred source to see more of our stories on Google. The microspheres (green), hepatocytes (magenta), and supporting fibroblasts (orange) assemble and reorganize into engineered liver ...

Differentiated hepatocyte organoids formed networks of small canals that allowed bile acid to pass, in a manner similar to human tissue. While organoids aim to mimic human organs, the liver’s ...

More than 10,000 Americans who suffer from chronic liver disease are on a waitlist for a liver transplant, but there are not enough donated organs for all of those patients. Additionally, many people ...

In mammals, the liver detects the body's energy demand at any given moment and mobilizes nutrient reserves to meet it. It is a vital function that is subdivided into multiple tasks: from releasing ...

Researchers used a microfluidic device to generate hydrogel microspheres of uniform shape and size. These spheres are then mixed with hepatocytes and injected into the body, where they form stable ...

In early-stage drug discovery, in vitro models are essential for generating clinically relevant data that expedite the progress of potential therapeutics into clinical trials. However, most ...