Dopamine—a neurotransmitter responsible for influencing motivation, pleasure, mood and learning in the brain—has experienced ...

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Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Methamphetamine addiction has a way of looping back on itself. A rush of pleasure pulls you in, cravings follow, and the brain learns that the drug is the fastest route to reward. Yet scientists still ...

A new doctoral dissertation shows that gambling disorder is linked to brain networks involved in self-control and brain ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

A researcher at UB's Research Institute on Addictions (RIA) has found a change in the brain that occurs after drug use and that may contribute to drug addiction. The finding, reported in the January ...

Heroin is one of the most addictive drugs in the world. It is an opioid that floods the brain with dopamine, a chemical that helps us feel pleasure. This causes a strong feeling of happiness, ...

Participants in a deep brain stimulation trial for drug addiction say the implants triggered compulsive behavior that upended their lives.