This article is based on a poster originally authored by Yongyang Huang, Ning Guo, Mackenzie Pierce, Leo Chan, Bo Lin and Yi Yang, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...

Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...

Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to identifying genetic perturbation patterns in cell images – potentially enabling ...

To isolate specific cell populations, researchers frequently employ fluorescence-activated cell sorting (FACS). While this flow cytometry-based technique analyzes the cells’ fluorescence, it cannot ...

Standard genetic sequencing approaches can tell you a lot about the genetic makeup and activity in a sample, like a piece of tissue or drop of blood. But they don't tell you where specific genetic ...

The CellVoyager CQ1 extracts rich features, making comprehensive high-content cellular image analysis possible, while the Nipkow Spinning Disk Confocal Technology enables high-speed scanning while ...

Fluorescence-based imaging methods have recorded many details of cell dynamics and behavior, but the full 3D orientation and position of fluorescently marked ensembles has remained difficult to ...

New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...