Medically reviewed by Brigid Dwyer, MD Key Takeaways The L5-S1 joint can be vulnerable to misalignment or injury. Common causes of pain at L5-S1 include disc herniation and spondylolisthesis.Pain from ...
Lower spine pain can develop due to sprains and strains of muscles or changes to the discs in the lower back. Conditions that affect the facet joints of the vertebrae may also cause lower spine pain.