Researchers at Lund University have created the most detailed map yet of the epigenome in pancreatic cells that regulate blood sugar, revealing key differences between people with and without type 2 ...

Using single-base resolution sequencing, the researchers systematically compared the DNA methylomes of HSCs from high-risk MDS patients with those from healthy donors. The analysis revealed distinct ...

Please provide your email address to receive an email when new articles are posted on . Researchers found associations between DNA methylation on imprinted genes at birth and metabolic dysfunction in ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation , a collaborative team led by Prof. Cao at the ...

Myelodysplastic syndromes (MDS) are malignant disorders arising from hematopoietic stem cells, yet the precise epigenetic abnormalities occurring in the primitive stem cells remain poorly understood.

At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...