The creation of a woolly-mouse embryo marks a significant leap in the field of de-extinction, bringing us one step closer to reviving the iconic woolly mammoth. By combining advanced gene-editing ...

In a world first, embryos have been sent to space so that scientists can study how zero-gravity affects a growing fetus. The mouse embryos were sent to the International Space Station to be raised by ...

Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...

A recent study published in Cell investigates how lamina-associated domains (LADs) contribute to nuclear genome organization in early-stage mouse embryos. Focusing on the zygote and two-cell stages, ...