New research has identified the enzyme glutamate dehydrogenase 1 (GLUD1) as a new therapeutic target for Duchenne muscular dystrophy (DMD). In preclinical DMD mouse models, investigators demonstrated ...

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the ...

Findings published in The American Journal of Pathology identify GLUD1 enzyme as a potential therapeutic target for muscle restoration through metabolic reprogramming, addressing clinically unmet need ...

What Is the Psoas Muscle? The psoas (pronounced so-ezz) muscles are two large muscles in your lower back. You have one on either side of your spine. They're the main muscular connection between your ...

A person may inherit the genetic changes responsible for muscular dystrophy. These genetic changes can also occur due to spontaneous genetic mutations. In either case, the disease is not preventable.

A growing body of research points to this overlooked structure as the missing piece in back pain treatment Back pain remains one of the most common health complaints worldwide, affecting an estimated ...

India, April 5 -- Myotonic dystrophy type 1 (DM1) is the leading form of muscular dystrophy that appears in adulthood. While it is best known for causing progressive muscle weakness and loss, the ...