Figure 1. Optical pooled screens and PerturbView. a) Optical pooled screens (OPS) use targeted in situ sequencing of perturbations to link phenotypes and genotypes from a pooled library, making it ...

Genetic screens are critical for the systematic identification of genes underlying cellular phenotypes. While pooling gene perturbations can greatly increase screening throughput, this approach was ...

RNA interference is an effective mechanism for gene silencing whereby double-stranded RNA triggers the cleavage and subsequent degradation of homologous transcript sequences. In this evolutionarily ...

Ebola virus executes its replication cycle through a tightly orchestrated sequence of events, but the host factors that govern the timing of these steps have remained poorly defined. In this talk, I ...

Semarion Ltd, a University of Cambridge spin-out company from the Cavendish Laboratory combining materials engineering and cell biology to tackle unmet drug screening needs, today introduced its ...