New research into the mechanism of the placebo effect sheds light on the brain circuitry involved in pain relief. The study, conducted by scientists at the University of North Carolina (UNC), Stanford ...

It’s not all in your head, but your expectations can sway your perception of pain intensity. Information about expectations — the driver of the placebo effect — travels from the cortex to groups of ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

UNC School of Medicine research reveals a pain control pathway from the cortex to cerebellum crucial for placebo analgesia – when the expectation of pain relief leads to pain alleviation without a ...

Share on Pinterest A recent study used computational methods to identify novel compounds that activate receptors involved in pain modulation without sedation. Peter Dazeley/Getty Images Research on ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Researchers have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain. Using a mouse model of painful osteoarthritis, they show that ...

René Descartes gave a colorful description of the mechanism of pain in the 17th Century: "Particles" of fire set in motion a spot on the skin of the foot, and by means of a "delicate thread" they open ...