Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

If you’ve ever had low back pain, you know how limiting it can be. And you’re not alone. According to the Centers for Disease Control and Prevention, as of 2019, back pain increases with age—from 28.4 ...

Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence ...

Men and women experience pain differently, and until now, scientists didn’t know why. New research says it may be in part due to differences in male and female nerve cells. Pain-sensing nerve cells ...

Without the ability to feel pain, life is more dangerous. To avoid injury, pain tells us to use a hammer more gently, wait for the soup to cool or put on gloves in a snowball fight. Those with rare ...

"Let's do it," Shelly Spears told her doctor. "I can no longer live like this." The "it" in this case was a procedure in which doctors would anesthetize an area of her back and then burn off a chunk ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...