High quality samples are key for data reproducibility and reliability. For biophysical protein characterization, quality samples are defined as those containing pure, soluble protein exhibiting ...

mRNA technologies have rapidly evolved into one of the most exciting and versatile classes of modern medicines, powering breakthroughs in vaccines and emerging therapies for metabolic, cardiovascular, ...

Ivonescimab is a next-generation bispecific antibody that simultaneously targets programmed cell death protein 1 (PD-1) and vascular endothelial growth factor (VEGF), two key molecules in the tumour ...

Aggregation is an important quality attribute of many protein-based biopharmaceuticals, including monoclonal antibodies (mAbs), that can influence product efficacy and safety; as such monitoring of ...

The variability in electrochemical activity within a battery electrode plays a critical role in defining its overall performance and lifespan. This can be determined by investigating bulk structural ...

The presence of inactive, empty capsids in potentially large quantities is one of the main challenges in AAV production. Quantifying the ratio of empty-full AAV capsids is currently ...

Refeyn, the company behind pioneering mass photometry technology, announces that mass photometry has been recognized by the US Pharmacopoeia (USP)—and referenced in the new draft USP general chapter ...

In this application note, discover how mass photometry can be used to analyze the fragmentation and aggregation of therapeutic antibodies in response to stressors like light, pH variations, and ...

Refeyn has announced that mass photometry has been recognized by the US Pharmacopeia (USP) – and referenced in the new draft USP general chapter <1067> – as a key orthogonal method for characterizing ...

Approximately 25 percent of proteins localize to membranes, where they act as receptors and signaling molecules in biological processes, including respiration, neurotransmission, and molecular ...

Osaka, Japan – Gene therapy is at the cutting edge of medicine, with exciting new products being developed and used to treat a wide variety of genetic diseases. However, one major roadblock to ...

MOST methods of heterochromatic photometry currently employed are based on dual optical systems, consisting of two beams of light which pass through appropriate filters and fall on two photo-cells. We ...