Holly has a degree in Medical Biochemistry from the University of Leicester. Her scientific interests include genomics, personalized medicine, and bioethics.View full profile Holly has a degree in ...

An artificial intelligence (AI) model has simulated half a billion years of molecular evolution to create the code for a previously unknown protein, according to a new study. The glowing protein, ...

The genetic code has given rise to the enormous diversity of proteins we see in nature—and rearranging the order of codons that make up a protein’s sequence leads to an immense variety of structure ...

Schematic of the T7-ORACLE system. The genome is maintained by the non-mutagenic host replisome (gray), while an orthogonal T7 replisome (red) maintains only a dedicated plasmid (OR) at 100,000-fold ...

A new platform combines rational protein design with continuous evolution to discover functional molecules more efficiently. In medicine and biotechnology, the ability to evolve proteins with new or ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

Northwestern Medicine scientists have developed a new experimental method to analyze conformational fluctuations in protein ...