For most of us, the sense of smell is an integral part of everyday life; it plays a critical role in providing information ...

Summary: For over a century, potassium ions were viewed as mere passengers in the brain—particles that flow through channels to generate electrical signals. However, a new discovery revealed that ...

A research team at Leipzig University has identified a mechanism in adhesion G protein-coupled receptors (adhesion GPCRs), a ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 diabetes mellitus and obesity. GLP-1 receptor ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...

Activation of the serotonin receptor, 5-HT1A, has been shown to regulate mood and cognition. The receptor is the primary target of buspirone, vilazodone, and gepirone, FDA-approved medications for the ...

Researchers have identified a receptor, Smoothened, that regulates how the adult brain locks in or overwrites learned behaviors by controlling the timing of neurotransmitter pauses in the striatum.

Opioid receptors are fantastic targets for treating pain—but unfortunately, the drugs that target them can be addictive. Because the molecules suppress breathing and heart function, those drugs can ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...