Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the ...

Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism. DNA, which stands for deoxyribonucleic ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

DNA replication is a tightly controlled process that copies the genetic code, allowing its instructions to be conveyed from one generation of cells to the next. In diseases like cancer, these ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

The power of artificial intelligence (AI) and advanced computing has made it possible to design genetic sequences encoding ...

A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.