Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing ...

The last time The Lancet Microbe featured an Editorial on CRISPR was in November 2020, to mark that year’s Nobel Prize in Chemistry, jointly awarded to Emmanuelle Charpentier and Jennifer A Doudna for ...

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could ...

Scientists say they have shed new light on how bacteria protect themselves from certain phage invaders -- by seizing genetic material from weakened, dormant phages and using it to 'vaccinate' ...

The global rise in antibiotic resistance is making bacterial infections harder to treat and increasing the risk of disease spread, severe illness, and death. Once considered miracle drugs, antibiotics ...

Using laboratory-evolved versions of CRISPR-associated transposases (CASTs) from bacteria, scientists at the Broad Institute and Columbia University were able to insert healthy genes into human cells ...

Antibiotics usually save lives—but against some bacteria, they can make things worse. That’s the case with the Shiga toxin–producing Escherichia coli, where bacterial death releases a flood of a ...

With such striking effects, many scientists see modulating the microbiomes as a promising avenue for improving human health and wellbeing. In recent years, researchers have shown that tweaking the ...

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...

Engineered bacteria reprogram tumor macrophages and direct copper into cancer cells, triggering cell death and systemic immunity without damaging healthy tissue. (Nanowerk Spotlight) Tumors do not ...