Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

Yale researchers are sifting through a mosaic of cells in a living animal — both normal cells and mutated cells — to better understand how cancer grabs a foothold. But they’re starting by studying ...