The mitochondrial genome of Trypanosoma brucei is uniquely organised as a kinetoplast, a highly complex network composed of thousands of minicircles and a smaller number of maxicircles. This structure ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. The publication of two papers ...

Enzymes, which are crucial to controlling how cells replicate in the human body, could be the very ingredient that encourages DNA to spontaneously mutate -- causing potentially permanent genetic ...

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

Better understanding of the mechanisms involved in DNA repair may pave the way for developing inhibitors to improve the effectiveness of radiation therapy. Nucleotide excision repair (NER) is a ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules. DNA is a molecule found in just about every living cell. Because ...

Researchers at the University of Bristol have caught DNA-copying enzymes generating long stretches of genetic code without ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...