Gene expression reveals that different types of human cell can work as a unit. These cellular modules, found in several tissues, change during disease. However, suitable computational methods are ...

The problem of cell type became clear to genome biologist Jason Buenrostro in 2013. He was studying a cell line derived from someone with cancer, trying to map out how the DNA was arranged in the ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...

A new CRISPR screen method developed at Scripps Research has the potential to improve studies into the genetic underpinnings of human diseases and disorders. The method was outlined in Cell, in a ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when lysosomes, the cellular sanitation machines responsible for those tasks, break down or ...