Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

The cold season is in full swing, throats are scratchy and noses are running. We feel ill and hope it is not the flu. The ...

Zika virus (ZIKV) is a mosquito-borne orthoflavivirus that can cause birth defects, including microcephaly, a condition in which head and brain size are significantly reduced at birth. The collective ...

Herpes simplex virus partially liquefies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a new study shows. The research centers on how the nucleus of each human cell ...

The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's ...

Researchers show how LGP2 binds viral RNA ends, moves along the strand, and helps MDA5 form filaments that amplify antiviral signaling. The findings clarify an early defense step and may inform ...

Prevention remains critical; but once symptoms appear, treatment options are extremely limited. Because rabies hides behind a complex molecular shield, it is nearly impossible to fight. “For more than ...

Zika virus hijacks a key protein implicated in brain development for its own replication. Researchers led by Associate Professor Priya Shah at the University of California, Davis (CA, USA), have ...