A key protein involved in fat metabolism has been found to do more than scientists once thought. Instead of just releasing fat, it helps maintain healthy fat tissue and balance in the body. When it’s ...

The common forms of type 2 diabetes are caused by a constellation of genetic and epigenetic factors and molecular changes related to diet; lifestyle, including lack of exercise and sleep; ...

A research team has identified a novel target responsible for aging-related chronic metabolic disorders. Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic ...

Transcriptomic phenotyping offers mechanistic insight into adipocyte biology and metabolic disease. A signature of adipocyte ...

New research from the University of Eastern Finland sheds light on the mechanisms associating obesity with inflammation by exploring tiny membrane particles, known as extracellular vesicles, secreted ...

In a recent preclinical study published in the Journal of Clinical Investigation, researchers in the United States of America investigated the role of the transcription factor KLF15 (short for Kruppel ...

Skin fibrosis is an often-painful condition wherein the skin thickens and hardens, making it difficult to move. And with no effective treatments currently available, patients are left with few avenues ...

Uncovering the mystery of why individuals born with mutations in the gene that encodes HSL—the cytosolic enzyme that releases energy from fat—lose fat instead of gaining it, Dominique Langin, PhD, ...

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders. A research team led by Professor Jong Kyoung Kim from the Department of Life Sciences ...

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders. A research team led by Professor Jong Kyoung Kim from the Department of Life Sciences ...