Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into ...

A retrospective study highlights the potential for encephalitis and other serious neurologic side effects over the course of ...

In this episode of Community Corner, Brittany Dulmage, MD, associate professor of dermatology and director of oncodermatology ...

Pliant Therapeutics (Nasdaq: PLRX) today announced the dosing of the first participant in the FORTIFY Phase 1b open-label indication expansion clinical trial of PLN-101095 in combination with ...

Immunotherapy has transformed cancer treatment by helping the body’s immune system recognize and attack cancer cells more ...

Immune checkpoint blockade (ICB) has reshaped modern immunotherapy by unleashing antitumor immune responses through targeting inhibitory immune checkpoints ...

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

Patients who develop myocarditis within the first month of receiving immune checkpoint inhibitor therapy are more likely to have MC fatality.

The tumor microenvironment (TME) is highly complex and dynamic, shaped by diverse immune and tumor cell interactions. CD markers and immune checkpoints provide complementary insights into these ...