Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

Problems in DNA replication can induce chromosome rearrangements that are often associated with pathological disorders. Natural elements such as unusual DNA structures, fragile zones and DNA-binding ...

Telomeres must overcome specific challenges to ensure their efficient replication. In yeast cells, telomeres are replicated in late S phase in agreement with the late firing of subtelomeric origins.

The replication crisis in psychology refers to concerns about the credibility of findings in psychological science. The term, which originated in the early 2010s, denotes that findings in behavioral ...

DNA polymerases are enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA. These enzymes are essential to DNA replication and usually work in pairs to create two ...