Complement Deficiencies Explained: C1–C4 vs C5–C9 vs PNH | USMLE Step 1 High-Yield
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Complement Deficiencies Explained: C1–C4 vs C5–C9 vs PNH | USMLE Step 1 High-Yield
Step exams love complement deficiencies—and this 30-second breakdown makes them impossible to miss. Learn how early complement defects (C1–C4) lead to recurrent pyogenic infections and SLE, why terminal complement loss (C5–C9) screams Neisseria, and how PIGA mutations cause PNH with intravascular hemolysis. These are classic USMLE Step 1 ...
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